BONE MARROW BIOPSY KIT, 2 x 250 mL

PRINCIPLE

Tissue fixation is mainly carried out by the immersion of the tissues into chemical agents (fixatives) in order to interrupt the degradation processes that occur after the cell death, and thus, it preserves the structures and composition of the tissue. Fixing agents have the ability to stop the enzyme activity, the process of tissue autolysis and the protein denaturation. Some fixatives can be used, likewise, as preservatives, but not in all cases can be ensured a long term preservation. The decalcification process consists in the removal of calcium salts from the tissues once they have been fi xed to prepare the samples for further histological
examination. A good decalcifi er should remove completely the calcium deposits without aff ecting the tissues nor generating any artefact in the tissues and not interfering in the further staining processes. Bone Marrow Biopsy Kit contents specific fixative solution and decalcifier for bone marrow biopsy processing which allow the preservation of the cellular structure and the performance of immunohistochemical or enzyme staining.