IMMUNOGLOBULIN A (Ig A), 24 mL

PRINCIPLE

The reagent allows quantifying the level of human IgA present in the sample by comparing the turbidimetric response produced with that obtained from the standard curve of known human IgA concentrations. The reagent is an antiserum anti-human IgA which reacts with the IgA of the serum giving protein aggregates. This aggregation process produces an increase in the Abs. of the system.

DIAGNOSTIC USE

The IgA is a dimmer form in secretions. It acts as a protector agent in front of the respiratory system, urinary tract and intestinal tract infections. The monomer form is found in serum and its specific role is still unclear; it may be important in virus neutralization. High levels of serum IgA are found in hepatic diseases, tuberculosis, and rheumatoid arthritis. Low levels are associated with immunodeficiencies congenital or acquired. A single test result can not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.