IMMUNOGLOBULIN G (Ig G), 24 mL

PRINCIPLE

The reagent allows quantifying the level of human IgG present in the sample by comparing the turbidimetric response produced with that obtained from the standard curve of known human IgG concentrations. The reagent is an antiserum anti-human IgG that reacts with the IgG of the serum giving protein aggregates. This aggregation process produces an increase in the Abs. of the system.

DIAGNOSTIC USE

Immunoglobulin G (75% of total Igs of serum) is the predominant serum immunoglobulin. It is of particular importance in the body's long-term defence against infection. High levels of serum IgG are found in response to chronic or recurrent infections, autoimmune diseases and hepatic diseases. IgG deficiency is associated with recurrent and occasionally severe pyogenic infections and with immunodeficiencies acquired or congenital. A single test result can not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.