RF TURBIDIMETRIC LATEX (1:5), KIT, 50 mL

PRINCIPLE

The turbidimetric RF LATEX reagent allows quantifying the rheumatoid factors present in the sera samples by comparing the turbidimetric response produced by these with those obtained from sample with known concentrations of rheumatoid factor.
The reagent consists of a latex particle suspension sensitised with human gamma globulin, capable of aggregation in the presence of rheumatoid factors. This aggregation process produces an increase in the size of the particles which in turn produces an increase in the absorbance of the system.

DIAGNOSTIC USE

In most patients suffering from evolutive chronic polyarthritis, the presences of macroglobulins, rheumatoid factors (RF), which are able to agglutinate inert particles sensitized with human gamma-globulin, are detected. The test of the latex agglutination allows distinguishing between this disease and the other one known as articular rheumatism or rheumatic fever, in which rheumatoid factors are not present.

Single test result could not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.