ALBUMIN, 2 x 250 mL

PRINCIPLE

At acidic pH, albumin specifi cally combined with bromocresol green (BCG) to form a colored complex that is determined photometrically. The color produced in the reaction is proportional to the concentration of albumin in the sample under optimal
assay conditions.

DIAGNOSTIC USE

Albumin is the most abundant protein in human plasma. Its principal funtions are source of endogenous amino acids, non-specific transport vehicle for nonpolar compounds and specially it contributes towards maintaining the colloid oncotic pressure. Albumin values decrease in severe infections, rheumatic fever, liver diseases (cirrhosis or chronic active hepatitis), dermatitis or severe burns, ascites, bad absorption processes or intestinal obstruction and in cases of renal diseases (nephrotic syndrome, lupus, diabetes mellitus, glomerulonephritis). The albumin levels are high in dehydration processes. Single test result could not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.