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For in vitro determination of LDL - cholesterol in serum.
| State | Liquid |
| Storage temp. | +2 / +8 ºC |
| Technique | Polyvinyl sulphate (PVS) method |
PRINCIPLE
LDL-cholesterol can be determined as the diff erence between total cholesterol and the cholesterol content of the supernatant after precipitation of the LDL fraction by polyvinyl sulphate (PVS) in the presence of polyethylene-glycol monomethyl ether.
DIAGNOSTIC USE
LDL proteins are low density lipoproteins that transport cholesterol, triglycerides and lipids in the blood. A high level of cholesterol bound to the LDL fraction, LDL cholesterol, is associated with myocardial infarction and cardiovascular disease.Other diseases that present high levels of LDL cholesterol are: nephrosis, diabetes, hypothyroidism or obesity.Single test result could not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.