HEMOGLOBIN, 3 x 100 mL

PRINCIPLE

Ferricyanide oxidizes the Fe(II) present in hemoglobin, oxyhemoglobin and carboxyhemoglobin, into Fe(III), giving rise to methaemoglobin which, in the presence of cyanide ion, produces cyanmethaemoglobin, a stable red compound that is photometrically determined.

DIAGNOSTIC USE

Hemoglobin is a blood protein with quaternary structure, red-colored and has a heme group and iron inside. Its main function is to transport oxygen from the respiratory organs to the tissues, carbon dioxide from the tissues to the lungs to remove it, and also participates in the regulation of blood pH. A hemoglobin level below normal values may be due to anemia, cancer, kidney disease,
bleeding, hemolysis or bone marrow damage. High hemoglobin values may be indicative of dehydration, renal and lung chronic disease, tumors or cardiopathies. A single test result could not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.