URIC ACID LIQUID, 1 x 100 mL

    994022



    To access the documentation you must be registered

    Register


    Conformité européenne In vitro diagnostic product

    For in vitro determination of Uric acid in serum, plasma or urine.

    State Liquid
    Storage temp. +2 / +8 ºC
    Technique Uricase - POD method

    PRINCIPLE

    The uric acid of the sample is degraded by the action of uricase to allantoin with the release of hydrogen peroxide. Quantification of hydrogen peroxide released is performed by Trinder reaction, wherein a coloured quinone compound is formed by reacting with 4-aminoantipyrine and the chromogen 3,5-dichloro-2-hydroxysulfonate in the presence of peroxidase (POD). The colour produced in the reaction is proportional to the concentration of uric acid of the sample under optimal assay conditions.

    DIAGNOSTIC USE

    Elevated uric acid values are found in kidney disease, gout, hyperthyroidism, malignancies and myeloproliferative diseases. Lower values than those usual ones are found in congenital disorders of metabolism as xanthinuria and in cases of poor purine intake.
    The usual range of values for healthy subjects is large, depending on the feed, age, sex, and also, it seems to be related to inherited genetic variations. A single test result cannot be used to make a clinical diagnosis. It should integrate clinical and laboratory data.